Acetic Acid → 1-tert-butyl 4-methyl 3-((1-(tert-butoxycarbonyl)-4-ethylpiperidin-4-ylamino)methyl)-1H-pyrrolo[2,3-b]pyridine-1,4-dicarboxylate

HRID 91448Notes

Reaction equation

HRID 91448 reaction equation
[C:43]([BH3-:44])#[N:45].[CH3:39][C:40](=[O:41])[OH:42].[CH3:47][OH:48].[CH:1](=[O:2])[c:3]1[cH:4][n:5]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[c:6]2[n:7][cH:8][cH:9][c:10]([C:12](=[O:13])[O:14][CH3:15])[c:11]12.[NH2:23][C:24]1([CH2:37][CH3:38])[CH2:25][CH2:26][N:27]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:28][CH2:29]1.[Na+:46]>>[CH2:1]([c:3]1[cH:4][n:5]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[c:6]2[n:7][cH:8][cH:9][c:10]([C:12](=[O:13])[O:14][CH3:15])[c:11]12)[NH:23][C:24]1([CH2:37][CH3:38])[CH2:25][CH2:26][N:27]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:28][CH2:29]1

Participants

7

Reactant 6

HCID 176Acetic AcidHCID 887MethanolHCID 923Sodium ionHCID 498716Cyano-borohydrideHCID 45095672tert-Butyl 4-amino-4-ethylpiperidine-1-carboxylateHCID 58293521HCID 58293521, compound

Product 1

HCID 672244961-tert-butyl 4-methyl 3-((1-(tert-butoxycarbonyl)-4-ethylpiperidin-4-ylamino)methyl)-1H-pyrrolo[2,3-b]pyridine-1,4-dicarboxylate

Sources & evidence

ORD record
ord-4b9eaee4136244158b60c6300dc3a5d1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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