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HRID914724

反应详情

EQUATION

反应方程式

HRID 914724 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)N1CCC[C@H]1CN
HCID1512533

tert-Butyl (2S)-2-(aminomethyl)pyrrolidine-1-carboxylate

C10H20N2O2

结构：CN(C)C=NC(=S)NCC1CCN(C(=O)OC(C)(C)C)CC1
HCID72474665

未命名化合物

PRODUCTS

生成物

1
结构：CN(C)C=NC(=S)NC[C@@H]1CCCN1C(=O)OC(C)(C)C
HCID86596520

未命名化合物

PROCEDURE

实验过程

2-(S)-(3-dimethylaminomethylene-thioureidomethyl)-pyrrolidine-1-carboxylic acid 1,1-dimethylethyl ester was prepared from (S)-2-(aminomethyl)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester according to the procedure described in Example A (4-(3-dimethylaminomethylene -thioureidomethyl)-piperidine-1-carboxylic acid tert-butyl ester). Purified by column chromatography on silica gel (2:1 to 3:1 ethyl acetate/hexane eluant). Yellow solid. MS: 315.4 (M+H)+

WORKUP

后处理

  1. customPurified by column chromatography on silica gel (2:1 to 3:1 ethyl acetate/hexane eluant)