HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Dichloropyridine → Tert-butyl 3-(5-chloro-2-pyridinyl)-3,8-diazabicyclo[3.2.1]octane-8-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Dichloropyridine | HCID 27685 | — |
| Reactant | 8-Boc-3,8-diaza-bicyclo(3.2.1)octane | HCID 15740908 | — |
| Product | Tert-butyl 3-(5-chloro-2-pyridinyl)-3,8-diazabicyclo[3.2.1]octane-8-carboxylate | HCID 69290423 | — |
Reaction Steps
tert-Butyl 3,8-diazabicyclo[3.2.1]octane-8-carboxylate, prepared as described in (J. Med. Chem., (1998) 41, 674), and 2,5-dichloropyridine were processed as described in Example 10A to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07265115B2 |
| Source dataset | uspto-grants-2007_09 |
| ORD ID | ord-8a0a06e05262405fa3465d877be9bc2e |
| Source note | uspto-grants-2007_09 |