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HRID914754

反应详情

EQUATION

反应方程式

HRID 914754 的结构方程式

REACTANTS

反应物

2
反应SMILES：Brc1cncc(Br)c1
HCID69369

3,5-Dibromopyridine

C5H3Br2N

反应SMILES：CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2
HCID11521263

(1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE

C10H18N2O2

PRODUCTS

产物

1
反应SMILES：CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2c1cncc(Br)c1
HCID12016224

未命名化合物

PROCEDURE

实验过程

tert-Butyl (1S,4S)-2,5-diazabicyclo [2.2.1]heptane-2-carboxylate, prepared as described in (J. Med. Chem., (1988) 31, 1598-1611), and 3,5-dibromopyridine (purchased from Avocado Research Chemicals, Ltd.) were coupled according to the procedure described in Example 1A to provide the title compound. MS (DCI/NH3) m/z 354 (M+H)+.