5-Chloro-1H-indole-2-carboxylic acid → HCID 69144190, compound

Participants

Reaction Steps

Prepared from 1-D-valinyl-4-(1-methylpiperidin-4-yl)-piperidine hydrochloride and 5-chloroindole-2-carboxylic acid using methods substantially equivalent to General Coupling Method 2. Purified and converted to the hydrochloride salt from by preparative reverse phase HPLC (YMC ODSA C18 5μ column, 5-95% CH3CN in H2O with 0.01% HCl) to give the HCl salt.

Provenance & Evidence