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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 914922Generated: October 30, 2026

HCID 22248599, compound → HCID 22248483, compound

https://huagongshe.com/reaction/914922

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22248599HCID 22248599—
CatalystHCID 178418390HCID 178418390—
SolventMethanolHCID 887—
ProductHCID 22248483HCID 22248483195.3%

Reaction Steps

After then dissolving 50 mg of the 3-benzyloxycarbonyl-8-(2-fluorophenyl)-7-oxo-3-azabicyclo[4.3.0]nonane in 30 ml of methanol, 100 mg of 10% palladium-carbon was added and the mixture was stirred for 4 days at room temperature under a hydrogen atmosphere (1 atm). The reaction mixture was filtered and the filtrate was distilled off under reduced pressure to obtain 62 mg of 8-(2-fluorophenyl)-7-oxo-3-azabicyclo[4.3.0]nonane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07265108B2
Source datasetuspto-grants-2007_09
ORD IDord-1357baf68a54438a8a8df704e5714ac9
Source noteuspto-grants-2007_09