HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-methylpyridine → 7-Methyl-3-(2-methyl-2-nitropropyl)imidazo[1,2-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-methylpyridine | HCID 1533 | — |
| Reactant | 2-Bromo-4-methyl4-nitropentanal | HCID 22038558 | — |
| Product | 7-Methyl-3-(2-methyl-2-nitropropyl)imidazo[1,2-a]pyridine | HCID 22038565 | 63.4% |
Reaction Steps
2-Amino-4-methylpyridine (2.2 g, 20.3 mmol) and 2-bromo-4-methyl-4-nitropentanal (20.3 mmol) are reacted as described in Amine 7 to give 3.0 g of 7-methyl-3-(2-methyl-2-nitropropyl)imidazo[1,2-a]pyridine (63%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07265127B2 |
| Source dataset | uspto-grants-2007_09 |
| ORD ID | ord-2cb0157631e44e6ea9379b84f6cb05dc |
| Source note | uspto-grants-2007_09 |