HCID 58958437, compound → HCID 58958436, compound

Participants

Reaction Steps

Tert-butyl 1-[({-5-[3-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl}amino)carbonyl]-4-piperidinylcarbamate 19-14 (0.016 g, 0.033 mmol) was dissolved in trifluoroacetic acid and stirred at room temperature until deblocking was complete. The trifluoroacetic acid was then removed under reduced pressure and the titled product 19-15 was isolated via lyophilization. Hi-Res MS: calc: 387.1097 found: 387.1092. 1H-NMR (DMSO): 7.94 ppm (s, 1H); 7.56 ppm (m, 3H); 7.26 ppm (d, 1H); 4.23 ppm (s, 2H); 3.27 ppm (s, 1H); 2.92 ppm (t, 2H); 1.91 ppm (d, 2H); 1.41 ppm (q, 2H).

Provenance & Evidence