HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-(aminomethyl)benzoate → Methyl 4-(acetamidomethyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-(aminomethyl)benzoate | HCID 571728 | — |
| Reactant | Morpholine-4-carboxylic acid [1-(4-cyano-2,6-diphenyl-piperidin-4-ylcarbamoyl)-3,3-dimethyl-butyl]-amide | HCID 22260506 | — |
| Reactant | Morpholine-4-carboxylic acid [1-(4-cyano-1,3-dimethyl-piperidin-4-ylcarbamoyl)-2-cyclohexyl-ethyl]-amide | HCID 22260549 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Methyl 4-(acetamidomethyl)benzoate | HCID 15550681 | — |
Reaction Steps
Methyl-4-(acetylamino-methyl)-benzoate was prepared from acetic acid and methyl 4-(aminomethyl)benzoate using a method analogous to that of Example 1-part (d). The crude N-acyl ester was saponified using a method analogous to that of Example 1-part (c). The crude product was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07265132B2 |
| Source dataset | uspto-grants-2007_09 |
| ORD ID | ord-5f10800767e641d7ba0d4f38fe923bb8 |
| Source note | uspto-grants-2007_09 |