Thionyl Chloride → HCID 69280234, compound
Reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:9]([CH3:16])=[C:10]([CH2:14]O)[N:11]([CH3:13])[N:12]=2)=[CH:4][CH:3]=1.S(Cl)([Cl:19])=O>>[Cl:19][CH2:14][C:10]1[N:11]([CH3:13])[N:12]=[C:8]([C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=2)[C:9]=1[CH3:16]Participants
3
Procedure
In analogy to the procedure described for example 1 b], [5-(4-chloro-phenyl)-2,4-dimethyl-2H-pyrazol-3-yl]-methanol was reacted with thionyl chloride for 20 min at 0° C. to give 5-chloromethyl-3-(4-chloro-phenyl)-1,4-dimethyl-1H-pyrazole as yellow oil.
Sources & evidence
- ORD record
- ord-2318b2d6409a40c99ffccbcda0df3629
- Source dataset
- uspto-grants-2007_09
- Patent number
- US07265149B2
Reaction notes
Loading…