Aluminium lithium hydride → HCID 69284532, compound

HRID 915400Notes

Reaction equation

HRID 915400 reaction equation
C([O:3][C:4]([C:6]1[N:7]([CH3:20])[N:8]=[C:9]([C:13]2[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=2)[C:10]=1[CH2:11][CH3:12])=O)C.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[Cl:19][C:16]1[CH:15]=[CH:14][C:13]([C:9]2[C:10]([CH2:11][CH3:12])=[C:6]([CH2:4][OH:3])[N:7]([CH3:20])[N:8]=2)=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 69283052HCID 69283052, compound

Product 1

HCID 69284532HCID 69284532, compound

Procedure

In analogy to the procedure described for example 1 a], 5-(4-chloro-phenyl)-4-ethyl-2-methyl-2H-pyrazole-3-carboxylic acid ethyl ester was reduced with lithium aluminium hydride to give [5-(4-chloro-phenyl)-4-ethyl-2-methyl-2H-pyrazol-3-yl]-methanol as colorless crystals.

Sources & evidence

ORD record
ord-e5b7015803b347cda726b098be213ea9
Source dataset
uspto-grants-2007_09
Patent number
US07265149B2

Reaction notes

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