HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 5-chloromethyl-1-methyl-3-(4-trifluoromethyl-phenyl)-1H-pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (1-Methyl-3-(4-(trifluoromethyl)phenyl)-1H-pyrazol-5-YL)methanol | HCID 44818671 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 5-chloromethyl-1-methyl-3-(4-trifluoromethyl-phenyl)-1H-pyrazole | HCID 21082224 | — |
Reaction Steps
In analogy to the procedure described for example 1 b], [2-methyl-5-(4-trifluoromethyl-phenyl)-2H-pyrazol-3-yl]-methanol (example 3 b]) was reacted with thionyl chloride in chloroform to yield 5-chloromethyl-1-methyl-3-(4-trifluoromethyl-phenyl)-1H-pyrazole as yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07265149B2 |
| Source dataset | uspto-grants-2007_09 |
| ORD ID | ord-1d0c236f492c49f3a574327873b64317 |
| Source note | uspto-grants-2007_09 |