HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrabutylammonium Fluoride → [2,4-dimethyl-5-(4-trifluoromethyl-phenyl)-2H-pyrazol-3-yl]-methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrabutylammonium Fluoride | HCID 2724141 | — |
| Reactant | 5-(tert-butyl-dimethyl-silanyloxymethyl)-1,4-dimethyl-3-(4-trifluoromethyl-phenyl)-1H-pyrazole | HCID 131726583 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | [2,4-dimethyl-5-(4-trifluoromethyl-phenyl)-2H-pyrazol-3-yl]-methanol | HCID 69283865 | — |
Reaction Steps
In analogy to the procedure described for example 2 e], 5-(tert-butyl-dimethyl-silanyloxymethyl)-1,4-dimethyl-3-(4-trifluoromethyl-phenyl)-1H-pyrazole was treated with tetrabutylammonium fluoride in THF to yield [2,4-dimethyl-5-(4-trifluoromethyl-phenyl)-2H-pyrazol-3-yl]-methanol as yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07265149B2 |
| Source dataset | uspto-grants-2007_09 |
| ORD ID | ord-7c9a5e5631684c24b68c23c99c063ab3 |
| Source note | uspto-grants-2007_09 |