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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 915454Generated: November 2, 2026

Lithium Hydroxide → {6-[1-methyl-5-(4-trifluoromethoxy-phenyl)-1H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid

https://huagongshe.com/reaction/915454

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactant{6-[1-methyl-5-(4-trifluoromethoxy-phenyl)-1H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid ethyl esterHCID 69282571—
Product{6-[1-methyl-5-(4-trifluoromethoxy-phenyl)-1H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acidHCID 69280252—

Reaction Steps

In analogy to the procedure described for example 1 f], {6-[1-methyl-5-(4-trifluoromethoxy-phenyl)-1H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid ethyl ester was treated with LiOH to obtain {6-[1-methyl-5-(4-trifluoromethoxy-phenyl)-1H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid as colorless solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07265149B2
Source datasetuspto-grants-2007_09
ORD IDord-17eb28fa75194f5bbcf9099d630f22b0
Source noteuspto-grants-2007_09