Methylhydrazine → HCID 13370538, compound

HRID 915456Notes

Reaction equation

HRID 915456 reaction equation
[CH2:1]([O:3][C:4](=[O:18])/[C:5](/O)=[CH:6]/[C:7]([C:9]1[CH:14]=[CH:13][C:12]([Cl:15])=[C:11]([Cl:16])[CH:10]=1)=O)[CH3:2].[CH3:19][NH:20][NH2:21]>C(O)C>[CH2:1]([O:3][C:4]([C:5]1[N:20]([CH3:19])[N:21]=[C:7]([C:9]2[CH:14]=[CH:13][C:12]([Cl:15])=[C:11]([Cl:16])[CH:10]=2)[CH:6]=1)=[O:18])[CH3:2].[CH2:1]([O:3][C:4]([C:5]1[CH:6]=[C:7]([C:9]2[CH:14]=[CH:13][C:12]([Cl:15])=[C:11]([Cl:16])[CH:10]=2)[N:20]([CH3:19])[N:21]=1)=[O:18])[CH3:2]

Participants

5

Reactant 2

HCID 6061MethylhydrazineHCID 178473083HCID 178473083, compound

Product 2

HCID 13370538HCID 13370538, compoundHCID 67452186HCID 67452186, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In analogy to the procedure described for example 4 b], (Z)-4-(3,4-dichloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic acid ethyl ester was reacted with methylhydrazine in ethanol under reflux conditions to give 5-(3,4-dichloro-phenyl)-2-methyl-2H-pyrazole-3-carboxylic acid ethyl ester as colorless crystals and 5-(3,4-dichloro-phenyl)-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester as colorless crystals.

Sources & evidence

ORD record
ord-43a697ce0c0e4dbfa95d9acce2206622
Source dataset
uspto-grants-2007_09
Patent number
US07265149B2

Reaction notes

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