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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 91578Generated: October 26, 2026

Acetonitrile → 2-Amino-3-cyano-5-[(4-trifluoromethylphenyl)ethynyl]pyrazine

https://huagongshe.com/reaction/91578

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
ReactantTriethylamineHCID 8471—
ReactantBenzene, 1-iodo-4-(trifluoromethyl)-HCID 67993—
ReactantCopper iodideHCID 83717—
Reactant2-Amino-3-cyano-5-ethynylpyrazineHCID 15335273—
Product2-Amino-3-cyano-5-[(4-trifluoromethylphenyl)ethynyl]pyrazineHCID 15335274—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-01c3b4e4088b46ed9a2e1b9a45782805
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)