HCID 68582071, compound → HCID 68581790, compound

Participants

Reaction Steps

A solution of compound 1.4 (540 mg, 0.75 mmol) in MeOHic NH3 (120 mL, saturated at 0° C.) was stirred in a bomb at 45° C. for 16 hr. The mixture was evaporated to dryness and then the residue co-evaporated with additional MeOH. Purification by silica gel column chromatography using 6-14% MeOH in dicholoromethane as eluent gave the desired compound 1.5 (244 mg) as an off-white solid.

Provenance & Evidence