4-Methylcyclohexanone → HCID 3505257, compound

HRID 915909Notes

Reaction equation

HRID 915909 reaction equation
[CH3:1][CH:2]1[CH2:7][CH2:6][C:5](=O)[CH2:4][CH2:3]1.[C:9]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])(=[O:12])[NH:10][NH2:11]>CCCCCC>[CH3:1][CH:2]1[CH2:7][CH2:6][C:5](=[N:11][NH:10][C:9]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12])[CH2:4][CH2:3]1

Participants

4

Reactant 2

HCID 115254-MethylcyclohexanoneHCID 70091tert-Butyl carbazate

Product 1

HCID 3505257HCID 3505257, compoundYield 89.1%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

To a 230 ml hexane solution of 23.6 ml (192 mmol) of 4-methylcyclohexanone, 25.5 g (192 mg) of t-butyl carbazate was added, followed by heating the mixture under reflux for 20 minutes. Then, the reaction mixture was brought to room temperature, and precipitated solids were collected by filtration to obtain 38.7 g (89%) of the captioned compound.

Workup

  1. temperatureby heating the mixture
  2. temperatureunder reflux for 20 minutes
  3. customwas brought to room temperature
  4. customprecipitated solids
  5. filtrationwere collected by filtration

Sources & evidence

ORD record
ord-7e2f6a7f5fcc437cbe294bd90aac1db7
Source dataset
uspto-grants-2007_09
Patent number
US07268128B2

Reaction notes

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