HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2,3-dihydro-1-benzofuran → 4-(5-Bromo-2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-2-trifluoromethylpentanoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2,3-dihydro-1-benzofuran | HCID 2776159 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | Ethyl 2-hydroxy-4-methyl-2-(trifluoromethyl)pent-4-enoate | HCID 17935595 | — |
| Solvent | Carbon Disulfide | HCID 6348 | — |
| Product | 4-(5-Bromo-2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-2-trifluoromethylpentanoic acid ethyl ester | HCID 58959953 | — |
Reaction Steps
4-(5-Bromo-2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-2-trifluoromethylpentanoic acid ethyl ester was prepared using the procedure described in Example 1 with 5-bromo-2,3-dihydrobenzofuran and 2-hydroxy-4-methyl-2-trifluoromethylpent-4-enoic acid ethyl ester in carbon disulfide with aluminum chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07268152B2 |
| Source dataset | uspto-grants-2007_09 |
| ORD ID | ord-3b1231a0b9f8450e974204fa1a0ea3e4 |
| Source note | uspto-grants-2007_09 |