HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-2-fluoro-5-(trifluoromethyl)benzyl bromide → 7-[3-(3-Chloro-2-fluoro-5-trifluoromethylbenzyl)-4,4,4-trifluoro-3-hydroxy-1,1-dimethylbutyl]-2,3-dihydrobenzofuran-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-2-fluoro-5-(trifluoromethyl)benzyl bromide | HCID 2773764 | — |
| Reactant | 7-(4,4,4-Trifluoro-1,1-dimethyl-3-oxobutyl)-2,3-dihydrobenzofuran-5-carbonitrile | HCID 69475026 | — |
| Product | 7-[3-(3-Chloro-2-fluoro-5-trifluoromethylbenzyl)-4,4,4-trifluoro-3-hydroxy-1,1-dimethylbutyl]-2,3-dihydrobenzofuran-5-carbonitrile | HCID 58959991 | — |
Reaction Steps
The title compound was prepared from 7-(4,4,4-trifluoro-1,1-dimethyl-3-oxobutyl)-2,3-dihydrobenzofuran-5-carbonitrile and 3-chloro-2-fluoro-5-trifluoromethylbenzyl bromide using the procedure described in Example 5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07268152B2 |
| Source dataset | uspto-grants-2007_09 |
| ORD ID | ord-21c12edf0a92453da9f9033c1aa594b8 |
| Source note | uspto-grants-2007_09 |