HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → Ammonia
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | HCID 58959766 | HCID 58959766 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Ammonia | HCID 222 | — |
| Product | HCID 58959789 | HCID 58959789 | — |
Reaction Steps
Prepared according to the procedure used for preparation 37 using methyl-3-{3-[(2R)-2-({(2R)-2-[4-(benzyloxy)-3-(hydroxymethyl)phenyl]-2-hydroxyethyl}amino)propyl]phenyl}propanoate (Preparation 58), substituting dichloromethane:methanol: 880 ammonia (95:5:0.5 changing to 90:10:1 by volume) as column eluent to give the title compound as a colourless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07268147B2 |
| Source dataset | uspto-grants-2007_09 |
| ORD ID | ord-492f2fba43d2488f805ea5350613e7f3 |
| Source note | uspto-grants-2007_09 |