4-t-Butylbenzenesulfonyl chloride → HCID 11328712, compound

Participants

Reaction Steps

The title compound was prepared from 1-(4-nitro-benzyl)-1H-indole-5-carboxylic acid methyl ester and 4-tert-butylbenzene sulfonyl chloride followed the procedure of Example 3 Step 2 as a light brown solid: 1H NMR (DMSO-d6) δ 1.24 (s, 9H), 5.33 (s, 2H), 6.59 (d, J=3.2 Hz, 1H), 7.02 (d, J=8.7 Hz, 2H), 7.07 (d, J=8.7 Hz, 2H), 7.45 (d, J=8.7 Hz, 1H), 7.51-7.54 (m, 3H), 7.65 (d, J=8.5 Hz, 2H), 7.69 (d, J=1.7 Hz, 1H), 8.21 (d, J=1.3 Hz, 1H), 10.23 (br s, 1H), 12.39 (br s, 1H); MS (ESI) m/z 463 (MH+), 461 ([M−H]−); HRMS calcd for C26H26N2O4S: 463.1690; found (ESI+): 463.1681.

Provenance & Evidence