HCID 12143941, compound → Dimethyl-{4-methyl-5-[2-methyl-3-(1-propylbutoxy)-2,4,5,6-tetrahydro-pyrazolo[3,4-b]pyridin-7-yl]-pyridin-2-yl}-amine

HRID 916224Notes

Reaction equation

HRID 916224 reaction equation
Cl[C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[C:4](C)[C:3]=1N1CCCC2C(=O)N(C)NC1=2.[CH3:21][N:22]([CH3:41])[C:23]1[N:28]=[CH:27][C:26]([N:29]2[CH2:34][CH2:33][CH2:32][C:31]3[C:35](=[O:39])[N:36]([CH3:38])[NH:37][C:30]2=3)=[C:25]([CH3:40])[CH:24]=1>>[CH3:21][N:22]([CH3:41])[C:23]1[CH:24]=[C:25]([CH3:40])[C:26]([N:29]2[CH2:34][CH2:33][CH2:32][C:31]3=[C:35]([O:39][CH:2]([CH2:7][CH2:6][CH3:8])[CH2:3][CH2:4][CH3:5])[N:36]([CH3:38])[N:37]=[C:30]23)=[CH:27][N:28]=1

Participants

3

Reactant 2

HCID 12143941HCID 12143941, compoundHCID 221362527-(6-Dimethylamino-4-methylpyridin-3-yl)-2-methyl-1,2,4,5,6,7-hexahydropyrazolo[3,4-b]pyridin-3-one

Product 1

HCID 22136275Dimethyl-{4-methyl-5-[2-methyl-3-(1-propylbutoxy)-2,4,5,6-tetrahydro-pyrazolo[3,4-b]pyridin-7-yl]-pyridin-2-yl}-amine

Procedure

Example 12c was prepared according to the procedure described in Example 12a, except that 7-(2-chloro-4,6-dimethylphenyl)-2-methyl-1,2,4,5,6,7-hexahydropyrazolo[3,4-b]pyridin-3-one was replaced by 7-(6-dimethylamino-4-methylpyridin-3-yl)-2-methyl-1,2,4,5,6,7-hexahydropyrazolo[3,4-b]pyridin-3-one.

Workup

  1. customExample 12c was prepared

Sources & evidence

ORD record
ord-70a5597d209d44538188dcc0b2a6dbcd
Source dataset
uspto-grants-2007_09
Patent number
US07268146B2

Reaction notes

Loading…