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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 91624Generated: October 25, 2026

Hydrochloric Acid → (RS)-3,5-difluoro-pyridine-2-carboxylic acid [3-(3-methyl-5-oxo-morpholin-3-yl)-phenyl]-amide

https://huagongshe.com/reaction/91624

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantHexafluorophosphateHCID 9886—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantDiisopropylethylamineHCID 81531—
ReactantO-benzotriazol-1-yl-tetramethyluroniumHCID 130500—
Reactant3,5-Difluoropyridine-2-carboxylic acidHCID 2783262—
Reactant5-(3-Amino-phenyl)-5-methyl-morpholin-3-oneHCID 58155258—
Product(RS)-3,5-difluoro-pyridine-2-carboxylic acid [3-(3-methyl-5-oxo-morpholin-3-yl)-phenyl]-amideHCID 66931532—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-42f1710c3b0c4debb93d96c1bc93f898
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)