Sodium Hydroxide → HCID 86612863, compound

HRID 916272Notes

Reaction equation

HRID 916272 reaction equation
[CH2:1]([O:17][CH2:18][CH2:19][N:20]([CH2:25][C:26]([OH:28])=[O:27])[CH2:21][C:22]([OH:24])=[O:23])[CH2:2][CH2:3][CH2:4][O:5][CH2:6][CH2:7][N:8]([CH2:13][C:14]([OH:16])=[O:15])[CH2:9][C:10]([OH:12])=[O:11].[OH-].[Na+].[NH3][Pt:32](Cl)(Cl)[NH3]>O>[Pt:32].[Pt:32].[CH2:4]([O:5][CH2:6][CH2:7][N:8]([CH2:9][C:10]([OH:12])=[O:11])[CH2:13][C:14]([OH:16])=[O:15])[CH2:3][CH2:2][CH2:1][O:17][CH2:18][CH2:19][N:20]([CH2:21][C:22]([OH:24])=[O:23])[CH2:25][C:26]([OH:28])=[O:27]

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 8469114913-33-8HCID 86612864HCID 86612864, compound

Product 1

HCID 86612863HCID 86612863, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
60 °C

Procedure

Butylenebis(oxyethylenenitrilo)tetraacetic acid (0.544 gm) is neutralized to pH about 9 using 1N NaOH (˜10 ml) to obtain a clear solution. This solution is then diluted to about 50 ml with water. This solution is then added dropwise (about 1 ml) to the cisplatin solution prepared above maintained at about 60° C. The entire reaction mixture is allowed to stir at this temperature (about 60° C.) for about 3 hours. The temperature is then reduced to about 50° C. and the reaction mixture is allowed to stir at this temperature for another 3 hours.

Workup

  1. customto obtain a clear solution
  2. customprepared
  3. customThe entire reaction mixture
  4. customis then reduced to about 50° C.
  5. stirringto stir at this temperature for another 3 hours

Sources & evidence

ORD record
ord-2bc4795c50144879aa25b76ab5a7301a
Source dataset
uspto-grants-2007_09
Patent number
US07268245B2

Reaction notes

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