反应详情

A Pyrex tube was charged with 1-chloro-4-nitronaphthalene (52 mg, 0.25 mmol) and 3,5-dimethylpiperidine (133 μL, 1.0 mmol) followed by acetonitrile (2 mL). The tube was capped and the reaction tube was exposed to microwave irradiation (180° C., 5 min). The reaction mixture was filtered and the solid washed with cold ethanol. If needed the compound was purified according to Purification method C. Yield: 58 mg (82%).

1. customThe tube was capped
2. customthe reaction tube was exposed to microwave irradiation (180° C., 5 min)
3. filtrationThe reaction mixture was filtered
4. washthe solid washed with cold ethanol
5. customwas purified
6. customaccording to Purification method C