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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 916337Generated: October 29, 2026

Phenyl(piperidin-4-yl)methanone → 4-(4-Benzoylpiperidin-1-yl)naphthalene-1-carbonitrile

https://huagongshe.com/reaction/916337

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenyl(piperidin-4-yl)methanoneHCID 226102—
Reactant1-Cyano-4-fluoronaphthaleneHCID 2736734—
Product4-(4-Benzoylpiperidin-1-yl)naphthalene-1-carbonitrileHCID 692260988%

Reaction Steps

The title compound (3 mg, 8% yield) was prepared as described for 196MBT2-4 from 1-cyano-4-fluoronaphthalene (20 mg, 0.117 mmol) and 4-benzoylpiperidine (89 mg, 0.468 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07268232B2
Source datasetuspto-grants-2007_09
ORD IDord-3c0b9d2cd4114abf8c04a3daba38762c
Source noteuspto-grants-2007_09