3-Butyn-2-amine, 2-methyl- → HCID 86607368, compound

HRID 916538Notes

Reaction equation

HRID 916538 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:19]=[C:20]([Cl:22])[CH:21]=1)[O:5][CH:6]([CH2:16][O:17][CH3:18])[C:7]([NH:9][C:10]([CH3:15])([CH3:14])[C:11]#[C:12]C)=[O:8].NC(C)(C)C#C.NC(C)(C)C#CC>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:19]=[C:20]([Cl:22])[CH:21]=1)[O:5][CH:6]([CH2:16][O:17][CH3:18])[C:7]([NH:9][C:10]([CH3:14])([CH3:15])[C:11]#[CH:12])=[O:8]

Participants

4

Reactant 3

HCID 763193-Butyn-2-amine, 2-methyl-HCID 114123462-Methylpent-3-yn-2-amineHCID 69114589HCID 69114589, compound

Product 1

HCID 86607368HCID 86607368, compound

Procedure

2-(3,5-Dichlorophenoxy)-3-methoxy-N-(3-methylbut-1-yn-3-yl)propionamide was prepared in a similar way to 2-(3,5-dichlorophenoxy)-3-methoxy-N-(4-methylpent-2-yn-4-yl)propionamide as described in Example 1 except that 3-amino-3-methylbut-1-yne (commercially available as 90% aqueous solution) was used in place of 4-amino-4-methyl pent-2-yne in Stage 4.

Sources & evidence

ORD record
ord-3f555933faad48b087c2aa249a019f4c
Source dataset
uspto-grants-2007_09
Patent number
US07271130B2

Reaction notes

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