3,4,5-Trimethylphenol → 2-(3,4,5-trimethylphenoxy)-3-methoxy-N-(4-methylpent-2-yn-4-yl)propionamide

Participants

Role	Name	HCID	Charge
Reactant	3,4,5-Trimethylphenol	HCID 10696	—
Reactant	2-bromo-3-methoxy-N-(4-methylpent-2-yn-4-yl)propionamide	HCID 21078405	—
Product	2-(3,4,5-trimethylphenoxy)-3-methoxy-N-(4-methylpent-2-yn-4-yl)propionamide	HCID 69114908	—

Reaction Steps

In a similar procedure to Example 3 Stage 2, 3,4,5-trimethylphenol was reacted with 2-bromo-N-(4-methylpent-2-yn-4-yl) 3-methoxypropionamide to give the title product as a colourless gum. 1H NMR (CDCl3) δ: 1.61(6H, s); 1.80(3H, s); 2.11(3H, s); 2.26(6H, s); 3.40(3H, s); 3.82(2H, m); 4.53(1H, t); 6.62(2H, s); 6.66(1H, s).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07271130B2
Source dataset	uspto-grants-2007_09
ORD ID	ord-685254be2e7443958f769769761593cb
Source note	uspto-grants-2007_09