alpha-D-Glucopyranosyl bromide, tetraacetate → HCID 69423446, compound

Participants

Reaction Steps

To a solution of 6-(N-acetylamino)-3-(4-ethylbenzyl)-1H-pyridin-2-one (0.034 g) in dichloromethane (2.5 mL) were added acetobromo-α-D-glucose (0.10 g) and silver carbonate (0.17 g), and the mixture was stirred under shading for 3 hours at 50° C. The insoluble material was removed by filtration, and the filtrate was concentrated under reduced pressure. The residue was purified by preparative thin layer chromatography on silica gel (developing solvent: hexane/ethyl acetate=1/2) to give 6-(N-acetylamino)-2-(2,3,4,6-tetra-O-acetyl-β-D-gluco-pyranosyloxy)-3-(4-ethylbenzyl)pyridine (0.081 g).

Provenance & Evidence