Potassium Carbonate → HCID 69421997, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 5-(4-methoxybenzyl)-2,6-dimethyl-3H-pyrimidin-4-one (0.30 g) in acetonitrile (6 mL) were added acetobromo-α-D-glucose (0.76 g) and potassium carbonate (0.27 g), and the mixture was stirred for 17 hours at 60° C. The insoluble material was removed by filtration, and the filtrate was concentrated under reduced pressure. The residue was purified by column chromatography on aminopropyl silica gel (eluent: hexane/ethyl acetate=1/1) and on silica gel (eluent: hexane/ethyl acetate=1/1-1/2) to give 4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)-5-(4-methoxybenzyl)-2,6-dimethylpyrimidine (0.24 g).

Provenance & Evidence