Sodium Methoxide → HCID 69423353, compound

Participants

Reaction Steps

To a solution of 4-(2,3,4,6-tetra-O-acetyl-β-D-gluco-pyranosyloxy)-5-(4-methoxybenzyl)-2,6-dimethylpyrimidine (0.24 g) in methanol (4 mL) was added sodium methoxide (28% solution in methanol, 0.040 mL), and the mixture was stirred for 50 minutes at room temperature. After the reaction mixture was concentrated under reduced pressure, the residue was purified by column chromatography on silica gel (eluent: dichloro-methane/methanol=7/1) to give 4-(β-D-glucopyranosyloxy)-5-(4-methoxybenzyl)-2,6-dimethylpyrimidine (0.11 g).

Provenance & Evidence