Sodium Methoxide → HCID 69422406, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 3-(2,3,4,6-tetra-O-acetyl-β-D-gluco-pyranosyloxy)-4-[4-(2-benzoyloxyethyl)benzyl]pyridine (0.086 g) in methanol (1 mL) was added sodium methoxide (28% solution in methanol, 0.008 mL), and the mixture was stirred for 23 hours at 25° C. After the reaction mixture was concentrated under reduced pressure, the residue was purified by column chromatography on silica gel (eluent: dichloromethane/methanol=4/1) to give 3-(β-D-glucopyranosyloxy)-4-[4-(2-hydroxy-ethyl)benzyl]pyridine (0.044 g).

Provenance & Evidence