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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 916617Generated: October 29, 2026

Hydrochloric Acid → HCID 12132981, compound

https://huagongshe.com/reaction/916617

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 12132980HCID 12132980—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 12132981HCID 12132981100%

Reaction Steps

Following the procedure of method 7C, methyl (2S)-3-hydroxy-2-[(1,2,3,4-tetrahydrocyclopenta[b]indol-5-ylcarbonyl)amino]propanoate (8.9 mmol, 2.7 g) was hydrogenated using 5% Pd/C (2 g) and concentrated HCl (10 mL) in methanol (25 mL) to yield the crude product (8.9 mmol, 2.7 g, quantitative).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07271163B2
Source datasetuspto-grants-2007_09
ORD IDord-6188e2ca2b0a4d7cb3f02c3de71f99d3
Source noteuspto-grants-2007_09