2-Nitrobenzoyl chloride → (4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(2-amino-phenyl)methanone

Participants

Role	Name	HCID	Charge
Reactant	2-Nitrobenzoyl chloride	HCID 11875	—
Reactant	(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-amino-phenyl)methanone	HCID 11859044	—
Reactant	5-Bromo-4-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine	HCID 86596499	—
Product	(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(2-amino-phenyl)methanone	HCID 67219556	—

Reaction Steps

The title compound was prepared from 2-Nitrobenzoyl chloride and 5-Bromo-4-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine by procedures analogous to those described for the preparation of (4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-amino-phenyl)-methanone. MS: 322.3 (MH+); HPLC Rf: 5.52 min. (HPLC method 4).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07271262B2
Source dataset	uspto-grants-2007_09
ORD ID	ord-ed8ee4f9bd234b6a86957483a19b45bd
Source note	uspto-grants-2007_09