4-Nitrobenzoyl chloride → (4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(4-amino-phenyl)-methanone

Participants

Role	Name	HCID	Charge
Reactant	4-Nitrobenzoyl chloride	HCID 8502	—
Reactant	(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-amino-phenyl)methanone	HCID 11859044	—
Reactant	5-Bromo-4-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine	HCID 86596499	—
Product	(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(4-amino-phenyl)-methanone	HCID 67219784	—

Reaction Steps

The title compound was prepared from 4-Nitrobenzoyl chloride and 5-Bromo-4-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine by procedures analogous to those described for the preparation of (4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-amino-phenyl)-methanone. MS: 322.3 (MH+); HPLC Rf: 4.45 min. (HPLC method 4).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07271262B2
Source dataset	uspto-grants-2007_09
ORD ID	ord-86fafc0017d74bbb90f9a4299d78ba2b
Source note	uspto-grants-2007_09