HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[2-(Benzyloxy)ethoxy]-4-(2-bromoethyl)benzene → 2-[4-(2-Bromoethyl)phenoxy]ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[2-(Benzyloxy)ethoxy]-4-(2-bromoethyl)benzene | HCID 68940841 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-[4-(2-Bromoethyl)phenoxy]ethanol | HCID 69384360 | — |
Reaction Steps
1-[2-(benzyloxy)ethoxy]-4-(2-bromoethyl)benzene in EtOAc (150 mL) and EtOH (50 mL) was hydrogenated over 10% Pd/C (530 mg) at room temperature and atmospheric pressure for 8 h. The catalyst was removed by filtration over Celite, washed with EtOAc and concentrated in vacuo to give the title compound (3.6 g). LCMS RT=2.82 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07271197B2 |
| Source dataset | uspto-grants-2007_09 |
| ORD ID | ord-dc5a031a0e4543a8a902e51c9fdb3279 |
| Source note | uspto-grants-2007_09 |