m-Chloroperbenzoic acid → HCID 69387116, compound

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Reaction Steps

A solution of (5R)-3-{2-[4-(2-{[3-(cyclopentylsulfinyl)benzyl]oxy}ethoxy)phenyl]ethyl}-5-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-1,3-oxazolidin-2-one (56 mg) in CH2Cl2 (2 ml) was cooled in an ice bath under a nitrogen atmosphere. To this was added 3-chloroperoxybenzoic acid (30 mg) and the resulting solution was allowed to warm to room temperature and stirred for 2 h. The solution was then washed with sodium sulphite, to remove any excess peroxide, and water. The combined organic layers were then dried (MgSO4) and concentrated in vacuo to give the title compound (70 mg). LCMS RT=3.70 min.

Provenance & Evidence