Potassium Cation → 5-Bromo-2-chloro-4-(4-chlorophenyl)pyridine

HRID 91695Notes

Reaction equation

HRID 91695 reaction equation
[Br:1][c:2]1[c:3]([I:9])[cH:4][c:5]([Cl:8])[n:6][cH:7]1.[CH3:26][O:27][CH2:28][CH2:29][O:30][CH3:31].[Cl:10][c:11]1[cH:12][cH:13][c:14]([B:17]([OH:18])[OH:19])[cH:15][cH:16]1.[K+:20].[K+:21].[O-:22][C:23]([O-:24])=[O:25].[cH:32]1[cH:33][cH:34][c:35]([P:36]([Pd:37]([P:38]([c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)([c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)([P:57]([c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)([c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[P:76]([c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)([c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)[c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)([c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)[c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)[cH:107][cH:108]1>>[Br:1][c:2]1[c:3](-[c:14]2[cH:13][cH:12][c:11]([Cl:10])[cH:16][cH:15]2)[cH:4][c:5]([Cl:8])[n:6][cH:7]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 80711,2-DimethoxyethaneHCID 19660Carbonate IonHCID 742994-Chlorophenylboronic acidHCID 218651405-Bromo-2-chloro-4-iodopyridineHCID 178420554HCID 178420554, compound

Product 1

HCID 579797375-Bromo-2-chloro-4-(4-chlorophenyl)pyridine

Sources & evidence

ORD record
ord-1726c797612f4d4ab78fd6181dd11a75
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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