3-Hydroxy-5-chloropyridine → HCID 58961610, compound

HRID 916952Notes

Reaction equation

HRID 916952 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:18]([C:19]2[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][CH:20]=2)=[CH:17][C:12]([C:13]([O:15][CH3:16])=[O:14])=[C:11](Cl)[N:10]=1.[Cl:27][C:28]1[CH:29]=[N:30][CH:31]=[C:32]([OH:34])[CH:33]=1>>[Cl:25][C:22]1[CH:23]=[CH:24][C:19]([C:18]2[C:9]([C:3]3[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=3[Cl:1])=[N:10][C:11]([O:34][C:32]3[CH:31]=[N:30][CH:29]=[C:28]([Cl:27])[CH:33]=3)=[C:12]([CH:17]=2)[C:13]([O:15][CH3:16])=[O:14])=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 5823053-Hydroxy-5-chloropyridineHCID 58961588HCID 58961588, compound

Product 1

HCID 58961610HCID 58961610, compound

Procedure

Using the procedure described in Example 84, methyl 6-(2,4-dichlorophenyl)-5-(4-chlorophenyl)-2-chloro-nicotinate Example 83 was reacted with 3-chloro-5-hydroxypyridine to afford the title compound: m/e=521 (M+3); Rt=4.65 min

Sources & evidence

ORD record
ord-ababadc7710949ca97add1aee622f0b5
Source dataset
uspto-grants-2007_09
Patent number
US07271266B2

Reaction notes

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