Dimethylformamide dimethyl acetal → HCID 69418376, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of the ketone product from Step A (11.79 g; 42.4 mmol) in DMF (150 mL) in an oven-dried round bottom flask was added N,N-dimethylformamide dimethyl acetal (22.5 mL; 169 mmol) under a nitrogen atmosphere. The reaction was stirred at 75° C. for 16 hours. Most of the volatiles were removed in vacuo to afford the crude product as a oil which was used in the next step without further purification.

Provenance & Evidence