Cesium carbonate → HCID 11604924, compound

HRID 917433Notes

Reaction equation

HRID 917433 reaction equation
Br[C:2]1[CH:3]=[C:4]([CH:25]=[CH:26][N:27]=1)[C:5]([NH:7][C:8]1[S:9][C:10]2[C:11]([N:19]3[CH2:24][CH2:23][O:22][CH2:21][CH2:20]3)=[N:12][CH:13]=[C:14]([O:17][CH3:18])[C:15]=2[N:16]=1)=[O:6].[C:28](=[O:31])([O-])[O-].[Cs+].[Cs+]>N1CCOCC1>[CH3:18][O:17][C:14]1[C:15]2[N:16]=[C:8]([NH:7][C:5](=[O:6])[C:4]3[CH:25]=[CH:26][N:27]=[C:2]([N:7]4[CH2:8][CH2:28][O:31][CH2:4][CH2:5]4)[CH:3]=3)[S:9][C:10]=2[C:11]([N:19]2[CH2:24][CH2:23][O:22][CH2:21][CH2:20]2)=[N:12][CH:13]=1

Participants

4

Reactant 2

HCID 10796Cesium carbonateHCID 865972552-bromo-N-(7-methoxy-4-morpholin-4-yl-thiazolo[5,4-c]pyridin-2-yl)isonicotinamide

Product 1

HCID 11604924HCID 11604924, compound

Reagents, catalysts & solvents 1

HCID 8083MorpholineSolvent

Procedure

From 2-bromo-N-(7-methoxy-4-morpholin-4-yl-thiazolo[5,4-c]pyridin-2-yl)-isonicotinamide with cesium carbonate in morpholine. ES-MS m/e (%): 457 (M+H+, 100).

Sources & evidence

ORD record
ord-e19743c624c246c59c2a7800a1082acb
Source dataset
uspto-grants-2007_09
Patent number
US07273865B2

Reaction notes

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