Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diisopropylethylamine → 1-Oxa-8-aza-spiro[4.5]decane-8-carboxylic acid (7-methoxy-4-morpholin-4-yl-thiazolo[5,4-c]pyridin-2-yl)-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 반응물 | 1-Oxa-8-azaspiro[4.5]decane, trifluoroacetate (9CI) | HCID 22507707 | — |
| 반응물 | (7-Methoxy-4-morpholin-4-yl-thiazolo[5,4-c]pyridin-2-yl)-carbamic acid phenyl ester | HCID 86597258 | — |
| 용매 | 1,1-Dichloroethane | HCID 6365 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 1-Oxa-8-aza-spiro[4.5]decane-8-carboxylic acid (7-methoxy-4-morpholin-4-yl-thiazolo[5,4-c]pyridin-2-yl)-amide | HCID 86597274 | — |
반응 단계
From (7-methoxy-4-morpholin-4-yl-thiazolo[5,4-c]pyridin-2-yl)-carbamic acid phenyl ester with 1-oxa-8-aza-spiro[4.5]decane trifluoroacetate and N,N-diisopropylethylamine in dichloroethane and tetrahydrofuran. ES-MS m/e (%): 434 (M+H+, 100).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07273865B2 |
| 출처 데이터셋 | uspto-grants-2007_09 |
| ORD ID | ord-751ab754016f484182b2efc0a72e1686 |
| 출처 메모 | uspto-grants-2007_09 |