HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → 4-Methoxymethyl-4-methyl-piperidine-1-carboxylic acid (7-methoxy-4-morpholin-4-yl-thiazolo[5,4-c]pyridin-2-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-Methoxymethyl-4-methylpiperidine trifluoroacetate | HCID 22507724 | — |
| Reactant | (7-Methoxy-4-morpholin-4-yl-thiazolo[5,4-c]pyridin-2-yl)-carbamic acid phenyl ester | HCID 86597258 | — |
| Solvent | 1,1-Dichloroethane | HCID 6365 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-Methoxymethyl-4-methyl-piperidine-1-carboxylic acid (7-methoxy-4-morpholin-4-yl-thiazolo[5,4-c]pyridin-2-yl)-amide | HCID 86597277 | — |
Reaction Steps
From (7-methoxy-4-morpholin-4-yl-thiazolo[5,4-c]pyridin-2-yl)-carbamic acid phenyl ester with 4-methoxymethyl-4-methyl-piperidine trifluoroacetate and N,N-diisopropylethylamine in dichloroethane and tetrahydrofuran. ES-MS m/e (%): 436 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07273865B2 |
| Source dataset | uspto-grants-2007_09 |
| ORD ID | ord-3732e5be3c6844b7934e6c3850ddf3ae |
| Source note | uspto-grants-2007_09 |