p-Anisoyl chloride → HCID 58962984, compound

HRID 917551Notes

Reaction equation

HRID 917551 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7](Cl)=O)=[CH:5][CH:4]=1.COC1C=C[C:17]([C:20]2[C:24]([C:25]([OH:27])=[O:26])=[C:23](C)[N:22](C)[N:21]=2)=CC=1>>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]2[N:22]([CH3:23])[N:21]=[C:20]([CH3:17])[C:24]=2[C:25]([OH:27])=[O:26])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 7477p-Anisoyl chlorideHCID 69006459HCID 69006459, compound

Product 1

HCID 58962984HCID 58962984, compound

Procedure

From 3.59 g of 4-methoxybenzoyl chloride, 1.97 g (59%) of a mixture of the title compound (major) and 3-(4-methoxyphenyl)-1,5-dimethyl-1H-pyrazole-4-carboxylic acid (minor) was prepared. H1-NMR(CD3OD, 500 MHz) for the title compound: δ 7.27 (2H, d, J=9 Hz), 7.03 (2H,d, J=9 Hz), 3.84 (3H, s), 3.60 (3H, s), 2.43 (3H, s).

Sources & evidence

ORD record
ord-bfc3ba1e0cc24f79b4c9f3ede9dbd571
Source dataset
uspto-grants-2007_09
Patent number
US07273882B2

Reaction notes

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