HCID 17848289, compound → HCID 14001095, compound

HRID 917653Notes

Reaction equation

HRID 917653 reaction equation
C([N:11]1[CH2:15][CH2:14][CH2:13][CH:12]1[CH2:16][O:17][CH2:18][O:19][CH3:20])(OCC1C=CC=CC=1)=O.[H][H]>CO.[C].[Pd]>[CH3:20][O:19][CH2:18][O:17][CH2:16][CH:12]1[CH2:13][CH2:14][CH2:15][NH:11]1

Participants

5

Reactant 2

HCID 17848289HCID 17848289, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 14001095HCID 14001095, compound

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 887MethanolSolvent

Procedure

To a solution of N-carbobenzoxy-2-methoxymethoxymethylpyrrolidine (prepared in the above (2)) 3.9 g in methanol 80 ml is added palladium-carbon 1 g at argon atmosphere. Hydrogen gas is blown through the mixture and the mixture is stirred at room temperature for 3 hours. After reaction catalyst is removed by filtration and the filtrate is concentrated in vacuo to give 2-methoxymethoxymethylpyrrolidine 2.02 g.

Workup

  1. customAfter reaction catalyst
  2. customis removed by filtration
  3. concentrationthe filtrate is concentrated in vacuo

Sources & evidence

ORD record
ord-3b16249f726945719610cd4240625f51
Source dataset
uspto-grants-2007_09
Patent number
US07273868B2

Reaction notes

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