1-[4-(1H-1,2,3-triazol-1-ylmethyl)phenyl]-2(1H,3H)-imidazolone → 1-[2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1,2,4-triazol-1-yl)propyl]-3-[4-(triazol-1-ylmethyl)phenyl]imidazol-2-one

HRID 91766Notes

Reaction equation

HRID 91766 reaction equation
[F:1][c:2]1[c:3]([C:9]2([CH2:13][n:14]3[n:15][cH:16][n:17][cH:18]3)[O:10][CH:11]2[CH3:12])[cH:4][cH:5][c:6]([F:8])[cH:7]1.[n:19]1([CH2:24][c:25]2[cH:26][cH:27][c:28](-[n:31]3[c:32](=[O:36])[nH:33][cH:34][cH:35]3)[cH:29][cH:30]2)[n:20][n:21][cH:22][cH:23]1>>[F:1][c:2]1[c:3]([C:9]([OH:10])([CH:11]([CH3:12])[n:33]2[c:32](=[O:36])[n:31](-[c:28]3[cH:27][cH:26][c:25]([CH2:24][n:19]4[n:20][n:21][cH:22][cH:23]4)[cH:30][cH:29]3)[cH:35][cH:34]2)[CH2:13][n:14]2[n:15][cH:16][n:17][cH:18]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1

Participants

3

Reactant 2

HCID 105861811-[4-(1H-1,2,3-triazol-1-ylmethyl)phenyl]-2(1H,3H)-imidazoloneHCID 147064491-((2-(2,4-Difluorophenyl)-3-methyl-2-oxiranyl)methyl)-1H-1,2,4-triazole

Product 1

HCID 4832871-[2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1,2,4-triazol-1-yl)propyl]-3-[4-(triazol-1-ylmethyl)phenyl]imidazol-2-one

Sources & evidence

ORD record
ord-28d3e69ffcd94b8f8d4eaf087b9540eb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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