Testosterone → 14958-66-8

Participants

Reaction Steps

An oxime of testosterone was prepared in accordance with the following procedure. A dry pyridine solution of testosterone (6.95 mmoles) and hydroxylamine hydrochloride (17.4 mmoles) was stirred at room temperature for 48 hours. The pyridine was removed in vacuo and the crystalline residue was recrystallized from methanol-water and from ethanol to yield 1.89 g (89%) of testosterone oxime, mp 207-210, indicated by tlc to be a mixture of the syn and anti oxime isomers.

Provenance & Evidence