Ammonia → HCID 21825595, compound

Participants

Reaction Steps

Methanol saturated with ammonia at 0° (ca 150 ml) was added to 5.71 g (0.010 mol) of 1 in a pressure bottle and kept at room temperature for 4 days. After removal of the solvent, water (30 ml) was added and the mixture was extracted with ether (six 20 ml portions). The solvent was removed and the compound crystallized from ethanol to give 2.25 g (92%) of 4: m.p. 150°-151°; [α]D25 -59.4° (c 1.00, water); nmr (DMSO-d6) δ 5.97 (d, 1, J1',2' 4.0 Hz, 1'--H).

Provenance & Evidence