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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 917854Generated: October 26, 2026

Heptafluorobutyryl Chloride → 5-(Trifluoromethyl)-3-nitro-2-(2,2,3,3,4,4,4-heptafluorobutyramido)pyridine

https://huagongshe.com/reaction/917854

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHeptafluorobutyryl ChlorideHCID 67810—
Reactant3-Nitro-5-(trifluoromethyl)pyridin-2-amineHCID 10608391—
Product5-(Trifluoromethyl)-3-nitro-2-(2,2,3,3,4,4,4-heptafluorobutyramido)pyridineHCID 20355488—

Reaction Steps

5-(Trifluoromethyl)-3-nitro-2-aminopyridine is reacted with perfluorobutyryl chloride to yield 5-(trifluoromethyl)-3-nitro-2-(2,2,3,3,4,4,4-heptafluorobutyramido)pyridine, which when hydrogenated yields 6-(trifluoromethyl)-1-hydroxy-2-(perfluoro-n-propyl)-1H-imidazo(4,5-b)pyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03968116
Source datasetuspto-grants-1976_07
ORD IDord-34aa9f59938d4df3906703af7dcc6339
Source noteuspto-grants-1976_07